PSMA3 抗体 (Internal Region)
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- 抗原 See all PSMA3 抗体
- PSMA3 (Proteasome Subunit Alpha Type 3 (PSMA3))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PSMA3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- PSMA3 Antibody detects endogenous levels of total PSMA3.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PSMA3, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PSMA3 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- PSMA3 (Proteasome Subunit Alpha Type 3 (PSMA3))
- 别名
- PSMA3 (PSMA3 产品)
- 别名
- HC8 antibody, PSC3 antibody, Psma3l antibody, psma3 antibody, im:6909944 antibody, zgc:114044 antibody, Lmpc8 antibody, proteasome subunit alpha 3 antibody, proteasome subunit alpha 3 L homeolog antibody, proteasome (prosome, macropain) subunit, alpha type 3 antibody, PSMA3 antibody, Psma3 antibody, psma3.L antibody, psma3 antibody
- 背景
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Description: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.
Gene: PSMA3
- 分子量
- 28kDa
- 基因ID
- 5684
- UniProt
- P25788
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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