ZIC1/2/3 抗体
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- 抗原 See all ZIC1/2/3 (Zic1/2/3/4/5) products
- ZIC1/2/3 (Zic1/2/3/4/5) (Zic Family Member 1/2/3/4/5 (Zic1/2/3/4/5))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZIC1/2/3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- ZIC1/2/3 antibody detects endogenous levels of total ZIC1/2/3
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ZIC1/2/3
- 亚型
- IgG
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anti-Zic Family Member 1/2/3/4/5 (Zic1/2/3/4/5) (Center) antibody
Zic1/2/3/4/5 适用: 人, 小鼠, 小鸡, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Zic Family Member 1/2/3/4/5 (Zic1/2/3/4/5) (AA 316-365) antibodyZic1/2/3/4/5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zic Family Member 1/2/3/4/5 (Zic1/2/3/4/5) (AA 281-330) antibodyZic1/2/3/4/5 适用: 人, 小鼠 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- ZIC1/2/3 (Zic1/2/3/4/5) (Zic Family Member 1/2/3/4/5 (Zic1/2/3/4/5))
- 别名
- ZIC1/2/3 (Zic1/2/3/4/5 产品)
- 背景
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Description: Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' (By similarity).
Gene: ZIC1
- 分子量
- 51kDa
- 基因ID
- 7545
- UniProt
- Q15915, O95409, O60481
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