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WRAP53 抗体 (Internal Region)

WRAP53 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6266051
发货至: 中国
  • 抗原 See all WRAP53 抗体
    WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))
    抗原表位
    • 15
    • 4
    • 3
    • 1
    • 1
    Internal Region
    适用
    人, 小鼠, 大鼠
    宿主
    • 29
    • 6
    克隆类型
    • 32
    • 3
    多克隆
    标记
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WRAP53 antibody is un-conjugated
    应用范围
    • 26
    • 13
    • 13
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    WRAP53 Antibody detects endogenous levels of total WRAP53.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human WRAP53, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product WRAP53 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))
    别名
    WRAP53 (WRAP53 产品)
    别名
    DKCB3 antibody, TCAB1 antibody, WDR79 antibody, Wdr79 antibody, BC021790 antibody, WD repeat containing antisense to TP53 antibody, WD repeat containing, antisense to TP53 antibody, WD repeat containing, antisense to Trp53 antibody, WRAP53 antibody, Wrap53 antibody
    背景

    Description: Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level, it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.

    Gene: WRAP53

    分子量
    72-75 kDa
    基因ID
    55135
    UniProt
    Q9BUR4
    途径
    Telomere Maintenance
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