WRAP53 抗体 (Internal Region)
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- 抗原 See all WRAP53 抗体
- WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WRAP53 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- WRAP53 Antibody detects endogenous levels of total WRAP53.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human WRAP53, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product WRAP53 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))
- 别名
- WRAP53 (WRAP53 产品)
- 别名
- DKCB3 antibody, TCAB1 antibody, WDR79 antibody, Wdr79 antibody, BC021790 antibody, WD repeat containing antisense to TP53 antibody, WD repeat containing, antisense to TP53 antibody, WD repeat containing, antisense to Trp53 antibody, WRAP53 antibody, Wrap53 antibody
- 背景
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Description: Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level, it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.
Gene: WRAP53
- 分子量
- 72-75 kDa
- 基因ID
- 55135
- UniProt
- Q9BUR4
- 途径
- Telomere Maintenance
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