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- 抗原 See all TRPV1 抗体
- TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRPV1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- VR1 Antibody detects endogenous levels of total VR1.
- 预测反应
- Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human VR1, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TRPV1 Primary Antibody
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anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 21-124) antibody
TRPV1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 21-124) antibodyTRPV1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 124-153), (N-Term) antibodyTRPV1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33721 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) antibodyTRPV1 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 824-838), (C-Term), (Intracellular) antibodyTRPV1 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 1-155) antibodyTRPV1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (3rd Extracellular Loop), (AA 605-619), (Cys616) antibody (Atto 488)TRPV1 适用: 大鼠 IHC, ICC, IF, LCI 宿主: 兔 Polyclonal Atto 488
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 1-153) antibodyTRPV1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 21-124) antibodyTRPV1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) (AA 531-541) antibodyTRPV1 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))
- 别名
- TRPV1 (TRPV1 产品)
- 别名
- si:dkey-9e15.2 antibody, VR.5'sv antibody, Vr1 antibody, Vr1l1 antibody, VR1 antibody, OTRPC1 antibody, TRPV1alpha antibody, TRPV1beta antibody, VR-1 antibody, transient receptor potential cation channel, subfamily V, member 1 antibody, transient receptor potential cation channel subfamily V member 1 antibody, trpv1 antibody, Trpv1 antibody, TRPV1 antibody
- 背景
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Description: Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca2+-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions ( pH <6) directly activate the channel. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis.
Gene: TRPV1
- 分子量
- 95kDa
- 基因ID
- 7442
- UniProt
- Q8NER1
- 途径
- Dicarboxylic Acid Transport
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