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U2AF2 抗体 (Internal Region)

U2AF59 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265832
发货至: 中国
  • 抗原 See all U2AF2 (U2AF59) 抗体
    U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
    抗原表位
    • 14
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 49
    • 24
    • 16
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 48
    • 1
    克隆类型
    • 47
    • 2
    多克隆
    标记
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This U2AF2 antibody is un-conjugated
    应用范围
    • 31
    • 18
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    U2AF2 Antibody detects endogenous levels of total U2AF2.
    预测反应
    Pig,Bovine,Horse,Sheep,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human U2AF2, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product U2AF59 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
    别名
    U2AF2 (U2AF59 产品)
    别名
    U2AF65 antibody, 65kDa antibody, u2af65 antibody, U2AF2 antibody, DDBDRAFT_0186947 antibody, DDBDRAFT_0233353 antibody, DDB_0186947 antibody, DDB_0233353 antibody, zgc:110115 antibody, U2 small nuclear RNA auxiliary factor 2 antibody, U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 antibody, U2 small nuclear RNA auxiliary factor 2 S homeolog antibody, RNA recognition motif-containing protein RRM antibody, Splicing factor U2AF 65 kDa subunit antibody, U2 small nuclear RNA auxiliary factor 2a antibody, U2AF2 antibody, U2af2 antibody, u2af2.S antibody, u2af2 antibody, u2af2a antibody
    背景

    Description: Plays a role in pre-mRNA splicing and 3'-end processing (PubMed:17024186). By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10. Positively regulates pre-mRNA 3'-end processing by recruiting the CFIm complex to cleavage and polyadenylation signals (PubMed:17024186).

    Gene: U2AF2

    分子量
    53kDa
    基因ID
    11338
    UniProt
    P26368
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