U2AF2 抗体 (Internal Region)
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- 抗原 See all U2AF2 (U2AF59) 抗体
- U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This U2AF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- U2AF2 Antibody detects endogenous levels of total U2AF2.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human U2AF2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product U2AF59 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
- 别名
- U2AF2 (U2AF59 产品)
- 别名
- U2AF65 antibody, 65kDa antibody, u2af65 antibody, U2AF2 antibody, DDBDRAFT_0186947 antibody, DDBDRAFT_0233353 antibody, DDB_0186947 antibody, DDB_0233353 antibody, zgc:110115 antibody, U2 small nuclear RNA auxiliary factor 2 antibody, U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 antibody, U2 small nuclear RNA auxiliary factor 2 S homeolog antibody, RNA recognition motif-containing protein RRM antibody, Splicing factor U2AF 65 kDa subunit antibody, U2 small nuclear RNA auxiliary factor 2a antibody, U2AF2 antibody, U2af2 antibody, u2af2.S antibody, u2af2 antibody, u2af2a antibody
- 背景
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Description: Plays a role in pre-mRNA splicing and 3'-end processing (PubMed:17024186). By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10. Positively regulates pre-mRNA 3'-end processing by recruiting the CFIm complex to cleavage and polyadenylation signals (PubMed:17024186).
Gene: U2AF2
- 分子量
- 53kDa
- 基因ID
- 11338
- UniProt
- P26368
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