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- 抗原 See all TSHZ3 (ZNF537) 抗体
- TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TSHZ3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- TSH3 Antibody detects endogenous levels of total TSH3.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TSH3, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ZNF537 Primary Antibody
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anti-Zinc Finger Protein 537 (ZNF537) (AA 466-515) antibody
ZNF537 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))
- 别名
- TSHZ3 (ZNF537 产品)
- 别名
- ZNF537 antibody, A630038G13Rik antibody, Tsh3 antibody, Zfp537 antibody, mKIAA1474 antibody, teashirt3 antibody, TSH3 antibody, teashirt zinc finger homeobox 3 antibody, teashirt zinc finger family member 3 antibody, TSHZ3 antibody, Tshz3 antibody
- 背景
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Description: Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s) (PubMed:19343227). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter (By similarity). Involved in the modulation of glutamatergic synaptic transmission and long-term synaptic potentiation (By similarity).
Gene: TSHZ3
- 分子量
- 119 kDa
- 基因ID
- 57616
- UniProt
- Q63HK5
- 途径
- Regulation of Muscle Cell Differentiation
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