Osteoprotegerin 抗体 (Internal Region)
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- 抗原 See all Osteoprotegerin (TNFRSF11B) 抗体
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Osteoprotegerin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Osteoprotegerin Antibody detects endogenous levels of total Osteoprotegerin.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Osteoprotegerin, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF11B Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 22-280) antibody
TNFRSF11B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 1-196) antibodyTNFRSF11B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 22-281) antibodyTNFRSF11B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) antibodyTNFRSF11B 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5G2 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 243-271) antibodyTNFRSF11B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) antibodyTNFRSF11B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) antibodyTNFRSF11B 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 1-196) antibodyTNFRSF11B 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 1-401) antibodyTNFRSF11B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 1-401) antibodyTNFRSF11B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
- 别名
- TNFRSF11B (TNFRSF11B 产品)
- 别名
- CD254 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, RANKL antibody, TRANCE antibody, hRANKL2 antibody, sOdf antibody, OCIF antibody, OPG antibody, TR1 antibody, Opg antibody, ocif antibody, opg antibody, tr1 antibody, TNF superfamily member 11 antibody, TNF receptor superfamily member 11b antibody, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antibody, TNF receptor superfamily member 11B antibody, tumor necrosis factor receptor superfamily member 11b S homeolog antibody, tumor necrosis factor receptor superfamily, member 11b antibody, TNFSF11 antibody, TNFRSF11B antibody, Tnfrsf11b antibody, tnfrsf11b.S antibody
- 物质类
- Chemical
- 背景
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Description: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
Gene: TNFRSF11B
- 分子量
- 46kDa
- 基因ID
- 4982
- UniProt
- O00300
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