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STAC3 抗体 (Internal Region)

STAC3 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265304
发货至: 中国
  • 抗原 See all STAC3 products
    STAC3 (SH3 and Cysteine Rich Domain 3 (STAC3))
    抗原表位
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 21
    • 11
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 18
    • 3
    克隆类型
    • 20
    • 1
    多克隆
    标记
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STAC3 antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    STAC3 Antibody detects endogenous levels of total STAC3.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human STAC3, corresponding to a region within the internal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    STAC3 (SH3 and Cysteine Rich Domain 3 (STAC3))
    别名
    STAC3 (STAC3 产品)
    别名
    9830125E18 antibody, SH3 and cysteine rich domain 3 antibody, STAC3 antibody, Stac3 antibody
    背景

    Description: Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca2+ release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels (PubMed:23736855, PubMed:29078335). Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane (By similarity). Slows down the inactivation rate of the calcium channel CACNA1C (in vitro) (PubMed:29078335).

    Gene: STAC3

    分子量
    42 kDa
    基因ID
    246329
    UniProt
    Q96MF2
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