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- 抗原 See all S100A12 抗体
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This S100A12 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), ELISA
- 特异性
- S100A12 Antibody detects endogenous levels of total S100A12
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human S100A12
- 亚型
- IgG
- Top Product
- Discover our top product S100A12 Primary Antibody
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anti-S100 Calcium Binding Protein A12 (S100A12) (AA 2-92) antibody
S100A12 适用: Pig IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) (AA 2-92) antibodyS100A12 适用: Cow IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) (AA 1-92) antibodyS100A12 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) (AA 1-92) antibodyS100A12 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) antibodyS100A12 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-812M unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) (AA 1-92) antibodyS100A12 适用: 人 IHC, WB, IP, ICC 宿主: 小鼠 Monoclonal 15# unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) antibodyS100A12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) antibodyS100A12 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) (AA 1-92) antibodyS100A12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F10 unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) antibodyS100A12 适用: 人 IHC, WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000 IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
- 别名
- S100A12 (S100A12 产品)
- 别名
- CAAF1 antibody, CAGC antibody, CGRP antibody, ENRAGE antibody, MRP-6 antibody, MRP6 antibody, p6 antibody, CO-AG antibody, EN-RAGE antibody, S100 calcium binding protein A12 antibody, protein S100-A12 antibody, S100A12 antibody, LOC101103771 antibody
- 背景
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Description: S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. Its proinflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER). Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of proinflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1. Acts as a monocyte and mast cell chemoattractant. Can stimulate mast cell degranulation and activation which generates chemokines, histamine and cytokines inducing further leukocyte recruitment to the sites of inflammation. Can inhibit the activity of matrix metalloproteinases, MMP2, MMP3 and MMP9 by chelating Zn2+ from their active sites. Possesses filariacidal and filariastatic activity. Calcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus.
Gene: S100A12
- 分子量
- 10kDa
- 基因ID
- 6283
- UniProt
- P80511
- 途径
- Toll-Like Receptors Cascades, S100 Proteins
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