Retinoic Acid Receptor gamma 抗体
-
- 抗原 See all Retinoic Acid Receptor gamma (RARG) 抗体
- Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Retinoic Acid Receptor gamma antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- Retinoic Acid Receptor / Antibody detects endogenous levels of Retinoic Acid Receptor /
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Retinoic Acid Receptor /
- 亚型
- IgG
- Top Product
- Discover our top product RARG Primary Antibody
-
-
- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
-
- 抗原
- Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))
- 别名
- Retinoic Acid Receptor (RARG 产品)
- 别名
- NR1B3 antibody, RARC antibody, AI385767 antibody, Nr1b3 antibody, RARD antibody, RARgamma2 antibody, RARG antibody, etID309710.23 antibody, etID33387.23 antibody, rarg antibody, rarg2 antibody, wu:fb01e02 antibody, wu:fb01f03 antibody, wu:fc35a09 antibody, nr1b3 antibody, RARgamma-B antibody, retinoic acid receptor gamma antibody, retinoic acid receptor, gamma antibody, retinoic acid receptor gamma a antibody, retinoic acid receptor gamma S homeolog antibody, retinoic acid receptor, gamma b antibody, RARG antibody, Rarg antibody, rarga antibody, rarg.S antibody, rargb antibody
- 背景
-
Description: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).
Gene: RARA
- 分子量
- 50kDa
- 基因ID
- 5914
- UniProt
- P10276, P10826
- 途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size
-