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- 抗原 See all RBBP6 抗体
- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RBBP6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- RBBP6 Antibody detects endogenous levels of total RBBP6.
- 预测反应
- Pig,Bovine,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RBBP6, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RBBP6 Primary Antibody
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anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 51-97) antibody
RBBP6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 1582-1691) antibodyRBBP6 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 2-150) antibodyRBBP6 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (full length) antibodyRBBP6 适用: 人, 小鼠 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 1-118) antibodyRBBP6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (N-Term) antibodyRBBP6 适用: 人, 小鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (C-Term) antibodyRBBP6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 395-444) antibodyRBBP6 适用: 人, 小鼠, 大鼠, Pig, Cow, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma Binding Protein 6 (RBBP6) (AA 1-118) antibodyRBBP6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
- 别名
- RBBP6 (RBBP6 产品)
- 别名
- MY038 antibody, P2P-R antibody, PACT antibody, RBQ-1 antibody, SNAMA antibody, 4933422O15Rik antibody, AI316869 antibody, BB233631 antibody, C030034J04Rik antibody, C77662 antibody, rbbp6 antibody, MGC75882 antibody, RBBP6 antibody, im:7158869 antibody, rbbp6l antibody, RB binding protein 6, ubiquitin ligase antibody, retinoblastoma binding protein 6, ubiquitin ligase antibody, retinoblastoma binding protein 6 antibody, RBBP6 antibody, Rbbp6 antibody, rbbp6 antibody
- 背景
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Description: E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53, may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth (By similarity). Regulates DNA-replication and the stability of chromosomal common fragile sites (CFSs) in a ZBTB38- and MCM10-dependent manner. Controls ZBTB38 protein stability and abundance via ubiquitination and proteasomal degradation, and ZBTB38 in turn negatively regulates the expression of MCM10 which plays an important role in DNA-replication (PubMed:24726359).
Gene: RBBP6
- 分子量
- 202 kDa
- 基因ID
- 5930
- UniProt
- Q7Z6E9
- 途径
- Regulatory RNA Pathways
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