RASIP1 抗体 (Internal Region)
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- 抗原 See all RASIP1 抗体
- RASIP1 (Ras Interacting Protein 1 (RASIP1))
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抗原表位
- Internal Region
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RASIP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- RASIP1 Antibody detects endogenous levels of total RASIP1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RASIP1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RASIP1 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- RASIP1 (Ras Interacting Protein 1 (RASIP1))
- 别名
- RASIP1 (RASIP1 产品)
- 别名
- RAIN antibody, 1110025D03Rik antibody, 2610025P08Rik antibody, AI853551 antibody, Rain antibody, Ras interacting protein 1 antibody, RASIP1 antibody, Rasip1 antibody
- 背景
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Description: Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.
Gene: RASIP1
- 分子量
- 103 kDa
- 基因ID
- 54922
- UniProt
- Q5U651
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