DLG4 抗体 (C-Term)
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- 抗原 See all DLG4 抗体
- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
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抗原表位
- C-Term
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适用
- 大鼠, 小鼠, 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DLG4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- PSD95 Antibody detects endogenous levels of total PSD95.
- 预测反应
- Zebrafish,Bovine,Horse,Sheep,Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PSD95, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product DLG4 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
- 别名
- DLG4 (DLG4 产品)
- 别名
- 11 antibody, CG1725 antibody, CG1730 antibody, CPD antibody, DLG antibody, DLG-A antibody, Discs-large antibody, Dlg antibody, Dlg-A antibody, Dlg1 antibody, DlgA antibody, Dmel\\CG1725 antibody, Drodlg antibody, PSD95 antibody, SAP97 antibody, anon-EST:Posey93 antibody, anon-WO03040301.258 antibody, anon-WO03040301.260 antibody, anon-WO03040301.268 antibody, d. lg.-1 antibody, dlg antibody, dlg-1 antibody, dlg-A antibody, dlgA antibody, dlgS97 antibody, l(1)10Bf antibody, l(1)G0276 antibody, l(1)G0342 antibody, l(1)G0456 antibody, l(1)G19 antibody, l(1)L11 antibody, l(1)bwn antibody, l(1)d.lg-1 antibody, l(1)d.lg.-1 antibody, l(1)discs large antibody, l(1)dlg antibody, l(1)dlg-1 antibody, l(1)dlg1 antibody, l(1)l.pr.-2 antibody, l(1)lpr-2 antibody, misb antibody, dlgh4 antibody, psd95 antibody, sap90 antibody, sap-90 antibody, LLGL1 antibody, Dlgh4 antibody, PSD-95 antibody, SAP90 antibody, SAP90A antibody, Sap90 antibody, SAP-90 antibody, DLG4 antibody, discs large 1 antibody, discs, large homolog 4 antibody, discs large MAGUK scaffold protein 4 antibody, discs, large homolog 4b (Drosophila) antibody, discs, large homolog 4 (Drosophila) antibody, dlg1 antibody, dlg4 antibody, DLG4 antibody, dlg4b antibody, Dlg4 antibody
- 背景
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Description: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression.
Gene: DLG4
- 分子量
- 105 kDa
- 基因ID
- 1742
- UniProt
- P78352
- 途径
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
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