PRKRA 抗体 (Internal Region)
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- 抗原 See all PRKRA 抗体
- PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRKRA antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- PRKRA Antibody detects endogenous levels of total PRKRA.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PRKRA, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PRKRA Primary Antibody
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anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (AA 1-313) antibody
PRKRA 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1B9-1A7 unconjugated
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) antibodyPRKRA 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) antibodyPRKRA 适用: 人 WB, IHC (p), IP, EIA 宿主: 小鼠 Monoclonal 1B9-1A7 unconjugated
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (AA 1-313) antibodyPRKRA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (AA 1-313) antibodyPRKRA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) antibodyPRKRA 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (AA 101-200) antibodyPRKRA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (AA 141-190) antibodyPRKRA 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (N-Term) antibodyPRKRA 适用: 人, Cow, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) (AA 1-314) antibodyPRKRA 适用: 人 WB, ELISA, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 1B9-1A7 unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))
- 别名
- PRKRA (PRKRA 产品)
- 别名
- PRKRA antibody, AV120107 antibody, PRK antibody, Pact antibody, RAX antibody, lear antibody, DYT16 antibody, PACT antibody, im:7151758 antibody, zgc:162619 antibody, dyt16 antibody, pact antibody, prkra-a antibody, prkra-b antibody, rax antibody, rbpa antibody, protein activator of interferon induced protein kinase EIF2AK2 antibody, protein kinase, interferon inducible double stranded RNA dependent activator antibody, protein kinase, interferon-inducible double stranded RNA dependent activator antibody, protein activator of interferon induced protein kinase EIF2AK2 L homeolog antibody, PRKRA antibody, Prkra antibody, prkra antibody, prkra.L antibody
- 背景
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Description: Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1. Promotes UBC9-p53/TP53 association and sumoylation and phosphorylation of p53/TP53 at 'Lys-386' at 'Ser-392' respectively and enhances its activity in a EIF2AK2/PKR-dependent manner (By similarity).
Gene: PRKRA
- 分子量
- 34kDa
- 基因ID
- 8575
- UniProt
- O75569
- 途径
- Regulatory RNA Pathways
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