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PLA2G2A 抗体 (Internal Region)

PLA2G2A 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264274
发货至: 中国
  • 抗原 See all PLA2G2A 抗体
    PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))
    抗原表位
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    人, 大鼠, 小鼠
    宿主
    • 31
    • 5
    • 2
    • 1
    克隆类型
    • 32
    • 7
    多克隆
    标记
    • 20
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLA2G2A antibody is un-conjugated
    应用范围
    • 23
    • 20
    • 11
    • 7
    • 2
    • 2
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    PLA2G2A Antibody detects endogenous levels of total PLA2G2A.
    预测反应
    Pig,Horse,Rabbit
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PLA2G2A, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PLA2G2A Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))
    别名
    PLA2G2A (PLA2G2A 产品)
    别名
    MOM1 antibody, PLA2 antibody, PLA2B antibody, PLA2L antibody, PLA2S antibody, PLAS1 antibody, sPLA2 antibody, EF antibody, Mom1 antibody, Pla2 antibody, sPla2-IIA antibody, phospholipase A2 group IIA antibody, phospholipase A2, group IIA (platelets, synovial fluid) antibody, PLA2G2A antibody, Pla2g2a antibody
    背景

    Description: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).

    Gene: PLA2G2A

    分子量
    16kDa
    基因ID
    5320
    UniProt
    P14555
    途径
    Stem Cell Maintenance, Inositol Metabolic Process
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