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PHF19 抗体 (Internal Region)

PHF19 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264174
发货至: 中国
  • 抗原 See all PHF19 抗体
    PHF19 (PHD Finger Protein 19 (PHF19))
    抗原表位
    • 9
    • 8
    • 6
    • 3
    • 1
    Internal Region
    适用
    • 26
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 24
    • 2
    克隆类型
    • 25
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This PHF19 antibody is un-conjugated
    应用范围
    • 26
    • 17
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    PHF19 Antibody detects endogenous levels of total PHF19.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PHF19, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PHF19 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    PHF19 (PHD Finger Protein 19 (PHF19))
    别名
    PHF19 (PHF19 产品)
    别名
    si:dkeyp-51b7.1 antibody, pcl3 antibody, MGC147603 antibody, MTF2L1 antibody, PCL3 antibody, TDRD19B antibody, 3110009G19Rik antibody, 3321402G02Rik antibody, PHD finger protein 19 antibody, Phf19 antibody, PHF19 antibody, phf19 antibody
    背景

    Description: Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem cell self-renewal. Also binds dimethylated at 'Lys-36' (H3K36me2). Isoform 1 and isoform 2 inhibit transcription from an HSV-tk promoter.

    Gene: PHF19

    分子量
    66 kDa
    基因ID
    26147
    UniProt
    Q5T6S3
    途径
    Stem Cell Maintenance
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