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KAT2B 抗体 (C-Term)

This anti-KAT2B antibody is a 兔 多克隆 antibody detecting KAT2B in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6264062
发货至: 中国

Quick Overview for KAT2B 抗体 (C-Term) (ABIN6264062)

抗原

See all KAT2B 抗体
KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This KAT2B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    特异性

    PCAF Antibody detects endogenous levels of total PCAF.

    预测反应

    Pig,Bovine,Horse,Sheep,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human PCAF, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

    别名

    KAT2B

    背景

    Description: Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY, PLK4 and TBX5. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Involved in heart and limb development by mediating acetylation of TBX5, acetylation regulating nucleocytoplasmic shuttling of TBX5 (PubMed:29174768). Acts as a negative regulator of centrosome amplification by mediating acetylation of PLK4 (PubMed:27796307).

    Gene: KAT2B

    分子量

    93kDa

    基因ID

    8850

    UniProt

    Q92831

    途径

    p53 Pathway, Regulation of Carbohydrate Metabolic Process
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