LEPREL2 抗体 (Internal Region)
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- 抗原 See all LEPREL2 抗体
- LEPREL2 (Leprecan Like Protein 2 (LEPREL2))
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LEPREL2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 特异性
- P3H3 Antibody detects endogenous levels of total P3H3.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human P3H3, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product LEPREL2 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- LEPREL2 (Leprecan Like Protein 2 (LEPREL2))
- 别名
- P3H3 (LEPREL2 产品)
- 别名
- GRCB antibody, HSU47926 antibody, P3H3 antibody, BC016431 antibody, Grcb antibody, P3h3 antibody, prolyl 3-hydroxylase 3 antibody, P3H3 antibody, P3h3 antibody
- 背景
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Description: Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Required for normal hydroxylation of lysine residues in type I collagen chains in skin, bone, tendon, aorta and cornea. Required for normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly. Apparently not required for normal prolyl 3-hydroxylation on collagen chains, possibly because it functions redundantly with other prolyl 3-hydroxylases.
Gene: P3H3
- 分子量
- 82 kDa
- 基因ID
- 10536
- UniProt
- Q8IVL6
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