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OAZ3 抗体 (Internal Region)

OAZ3 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263789
发货至: 中国
  • 抗原 See all OAZ3 抗体
    OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))
    抗原表位
    • 5
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 14
    • 1
    克隆类型
    • 15
    多克隆
    标记
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OAZ3 antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB)
    特异性
    OAZ3 Antibody detects endogenous levels of total OAZ3.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human OAZ3, corresponding to a region within the internal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))
    别名
    OAZ3 (OAZ3 产品)
    别名
    Az3 antibody, Oaz-t antibody, AZ3 antibody, OAZ-t antibody, TISP15 antibody, Az-3 antibody, ornithine decarboxylase antizyme 3 antibody, OAZ3 antibody, Oaz3 antibody
    背景

    Description: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity (PubMed:17900240). Stabilizes AZIN2 by interfering with its ubiquitination. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. Probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells (By similarity).

    Gene: OAZ3

    分子量
    27 kDa
    基因ID
    51686
    UniProt
    Q9UMX2
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