NPHP1 抗体 (Internal Region)
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- 抗原 See all NPHP1 抗体
- NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NPHP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- NPHP1 Antibody detects endogenous levels of total NPHP1.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NPHP1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NPHP1 Primary Antibody
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
- 别名
- NPHP1 (NPHP1 产品)
- 别名
- JBTS4 antibody, NPH1 antibody, SLSN1 antibody, nephrocystin-1 antibody, NPHP1 antibody, im:7162391 antibody, wu:fi59g07 antibody, zgc:152930 antibody, Nphp1 antibody, nephrocystin 1 antibody, nephronophthisis 1 (juvenile) homolog (human) antibody, nephronophthisis 1 (juvenile) L homeolog antibody, nephronophthisis 1 antibody, nephrocystin-1 antibody, NPHP1 antibody, Nphp1 antibody, nphp1.L antibody, nphp1 antibody, LOC100725987 antibody
- 背景
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Description: Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity). Seems to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role in the regulation of intraflagellar transport (IFT) during cilia assembly. Required for normal retina development. In connecting photoreceptor cilia influences the movement of some IFT proteins such as IFT88 and WDR19. Involved in spermatogenesis (By similarity).
Gene: NPHP1
- 分子量
- 83 kDa
- 基因ID
- 4867
- UniProt
- O15259
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