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NPHP1 抗体 (Internal Region)

NPHP1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263699
发货至: 中国
  • 抗原 See all NPHP1 抗体
    NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
    抗原表位
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 28
    • 14
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 28
    • 1
    克隆类型
    • 28
    • 1
    多克隆
    标记
    • 15
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NPHP1 antibody is un-conjugated
    应用范围
    • 18
    • 11
    • 8
    • 5
    • 4
    • 2
    Western Blotting (WB), ELISA
    特异性
    NPHP1 Antibody detects endogenous levels of total NPHP1.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human NPHP1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product NPHP1 Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
    别名
    NPHP1 (NPHP1 产品)
    别名
    JBTS4 antibody, NPH1 antibody, SLSN1 antibody, nephrocystin-1 antibody, NPHP1 antibody, im:7162391 antibody, wu:fi59g07 antibody, zgc:152930 antibody, Nphp1 antibody, nephrocystin 1 antibody, nephronophthisis 1 (juvenile) homolog (human) antibody, nephronophthisis 1 (juvenile) L homeolog antibody, nephronophthisis 1 antibody, nephrocystin-1 antibody, NPHP1 antibody, Nphp1 antibody, nphp1.L antibody, nphp1 antibody, LOC100725987 antibody
    背景

    Description: Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity). Seems to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role in the regulation of intraflagellar transport (IFT) during cilia assembly. Required for normal retina development. In connecting photoreceptor cilia influences the movement of some IFT proteins such as IFT88 and WDR19. Involved in spermatogenesis (By similarity).

    Gene: NPHP1

    分子量
    83 kDa
    基因ID
    4867
    UniProt
    O15259
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