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GRIN2C 抗体 (Internal Region)

GRIN2C 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263663
发货至: 中国
  • 抗原 See all GRIN2C 抗体
    GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
    抗原表位
    • 8
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 32
    • 21
    • 20
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 45
    • 2
    克隆类型
    • 47
    多克隆
    标记
    • 32
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRIN2C antibody is un-conjugated
    应用范围
    • 33
    • 13
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    NMDA epsilon 3 Antibody detects endogenous levels of total NMDA epsilon 3.
    预测反应
    Pig,Bovine,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human NMDA epsilon 3, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product GRIN2C Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
    别名
    GRIN2C (GRIN2C 产品)
    别名
    GRIN2C antibody, NMDAR2C antibody, il12rb2l antibody, il-12rb2.b antibody, nr2c antibody, GluN2C antibody, NR2C antibody, glutamate ionotropic receptor NMDA type subunit 2C antibody, interleukin 12 receptor, beta 2a, like antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2C S homeolog antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2C antibody, glutamate receptor, ionotropic, NMDA2C (epsilon 3) antibody, GRIN2C antibody, il12rb2l antibody, grin2c.S antibody, grin2c antibody, Grin2c antibody
    背景

    Description: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:26875626). Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable). Plays a role in regulating the balance between excitatory and inhibitory activity of pyramidal neurons in the prefrontal cortex. Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning (By similarity).

    Gene: GRIN2C

    分子量
    134 kDa
    基因ID
    2905
    UniProt
    Q14957
    途径
    Synaptic Membrane
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