KCNQ1 抗体 (C-Term)
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- 抗原 See all KCNQ1 抗体
- KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNQ1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- KCNQ1 Antibody detects endogenous levels of total KCNQ1.
- 预测反应
- Horse,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human KCNQ1, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product KCNQ1 Primary Antibody
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anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody
KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) unconjugated
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (HRP)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) HRP
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (FITC)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) FITC
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (Biotin)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) Biotin
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (PE)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) PE
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (APC)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) APC
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (PerCP)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) PerCP
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (Atto 488)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) Atto 488
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (Atto 594)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) Atto 594
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (Atto 390)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) Atto 390
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
- 别名
- KCNQ1 (KCNQ1 产品)
- 别名
- ATFB1 antibody, ATFB3 antibody, JLNS1 antibody, KCNA8 antibody, KCNA9 antibody, KVLQT1 antibody, Kv1.9 antibody, Kv7.1 antibody, LQT antibody, LQT1 antibody, RWS antibody, SQT2 antibody, WRS antibody, CG12215 antibody, CG12915 antibody, CG33135 antibody, DKCNQ antibody, Dmel\\CG33135 antibody, dKCNQ antibody, kcnq1 antibody, KCNQ1 antibody, kqt-3 antibody, kv7.1 antibody, Kvlqt1 antibody, KvLQT-1 antibody, kcnq1-A antibody, xkvlqt1 antibody, zgc:158384 antibody, AW559127 antibody, Kcna9 antibody, KvLQT1 antibody, potassium voltage-gated channel subfamily Q member 1 antibody, KCNQ potassium channel antibody, potassium voltage-gated channel, KQT-like subfamily, member 1 antibody, potassium channel, voltage gated KQT-like subfamily Q, member 1 antibody, voltage gated potassium channel subunit antibody, potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog antibody, potassium voltage-gated channel, subfamily Q, member 1 antibody, KCNQ1 antibody, KCNQ antibody, kcnq1 antibody, Kcnq1 antibody, kcnq1.L antibody
- 背景
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Description: Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity) (PubMed:10646604). Associates with KCNE beta subunits that modulates current kinetics (By similarity) (PubMed:9312006, PubMed:9108097, PubMed:8900283, PubMed:10646604, PubMed:11101505, PubMed:19687231). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity) (PubMed:9312006, PubMed:9108097, PubMed:8900283, PubMed:10646604, PubMed:11101505). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac repolarization by associating with KCNE1 to form the I(Ks) cardiac potassium current that increases the amplitude and slows down the activation kinetics of outward potassium current I(Ks) (By similarity) (PubMed:9312006, PubMed:9108097, PubMed:8900283, PubMed:10646604, PubMed:11101505). Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current (PubMed:10713961). When associated with KCNE3, forms the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions (PubMed:10646604). This interaction with KCNE3 is reduced by 17beta-estradiol, resulting in the reduction of currents (By similarity). During conditions of increased substrate load, maintains the driving force for proximal tubular and intestinal sodium ions absorption, gastric acid secretion, and cAMP-induced jejunal chloride ions secretion (By similarity). Allows the provision of potassium ions to the luminal membrane of the secretory canaliculus in the resting state as well as during stimulated acid secretion (By similarity). When associated with KCNE2, forms a heterooligomer complex leading to currents with an apparently instantaneous activation, a rapid deactivation process and a linear current-voltage relationship and decreases the amplitude of the outward current (PubMed:11101505). When associated with KCNE4, inhibits voltage-gated potassium channel activity (PubMed:19687231). When associated with KCNE5, this complex only conducts current upon strong and continued depolarization (PubMed:12324418). Also forms a heterotetramer with KCNQ5, has a voltage-gated potassium channel activity (PubMed:24855057). Binds with phosphatidylinositol 4,5-bisphosphate (PubMed:25037568).
Gene: KCNQ1
- 分子量
- 61kDa
- 基因ID
- 3784
- UniProt
- P51787
- 途径
- Negative Regulation of Hormone Secretion, Sensory Perception of Sound
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