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KCNJ10 抗体 (Internal Region)

KCNJ10 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262748
发货至: 中国
  • 抗原 See all KCNJ10 抗体
    KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))
    抗原表位
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 48
    • 15
    • 15
    • 1
    人, 大鼠, 小鼠
    宿主
    • 44
    • 3
    • 1
    克隆类型
    • 46
    • 2
    多克隆
    标记
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNJ10 antibody is un-conjugated
    应用范围
    • 34
    • 21
    • 19
    • 15
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    KCNJ10 Antibody detects endogenous levels of total KCNJ10.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human KCNJ10, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product KCNJ10 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))
    别名
    KCNJ10 (KCNJ10 产品)
    别名
    kir1.2 antibody, kir4.1 antibody, birk-10 antibody, MGC145926 antibody, BIR10 antibody, BIRK-1 antibody, Kir1.2 antibody, Kir4.1 antibody, BIRK-10 antibody, KCNJ13-PEN antibody, KIR1.2 antibody, KIR4.1 antibody, SESAME antibody, potassium channel, inwardly rectifying subfamily J, member 10 L homeolog antibody, potassium voltage-gated channel subfamily J member 10 antibody, potassium channel, inwardly rectifying subfamily J, member 10 antibody, potassium inwardly-rectifying channel, subfamily J, member 10 antibody, kcnj10.L antibody, KCNJ10 antibody, kcnj10 antibody, Kcnj10 antibody
    背景

    Description: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). In the kidney, together with KCNJ16, mediates basolateral K+ recycling in distal tubules, this process is critical for Na+ reabsorption at the tubules.

    Gene: KCNJ10

    分子量
    43 kDa
    基因ID
    3766
    UniProt
    P78508
    途径
    Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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