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HOMER1 抗体 (Internal Region)

HOMER1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262337
发货至: 中国
  • 抗原 See all HOMER1 抗体
    HOMER1 (Homer Homolog 1 (HOMER1))
    抗原表位
    • 10
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 39
    • 21
    • 9
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 34
    • 4
    • 1
    克隆类型
    • 36
    • 3
    多克隆
    标记
    • 25
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HOMER1 antibody is un-conjugated
    应用范围
    • 28
    • 12
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    HOMER1 Antibody detects endogenous levels of total HOMER1.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human HOMER1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product HOMER1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    HOMER1 (Homer Homolog 1 (HOMER1))
    别名
    HOMER1 (HOMER1 产品)
    别名
    HOMER antibody, HOMER1A antibody, HOMER1B antibody, HOMER1C antibody, SYN47 antibody, Ves-1 antibody, HOMER1 antibody, PSD-Zip45 antibody, homer1 antibody, zgc:100854 antibody, zgc:92844 antibody, HOMER1F antibody, Vesl-1 antibody, homer antibody, xhomer1 antibody, BEST:LD03829 antibody, CG11324 antibody, Dhom antibody, Dhomer antibody, Dm Homer antibody, Dmel\CG11324 antibody, Dvh antibody, Hom antibody, Homer antibody, LD03829 antibody, dhom antibody, homer scaffolding protein 1 antibody, homer scaffolding protein 1b antibody, homer scaffolding protein 1 L homeolog antibody, CG11324 gene product from transcript CG11324-RD antibody, HOMER1 antibody, Homer1 antibody, homer1b antibody, homer1.L antibody, homer antibody
    背景

    Description: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.

    Gene: HOMER1

    分子量
    46-48 kDa
    基因ID
    9456
    UniProt
    Q86YM7
    途径
    Skeletal Muscle Fiber Development
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