HECW1 抗体 (Internal Region)
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- 抗原 See all HECW1 抗体
- HECW1 (HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1))
- 抗原表位
- Internal Region
- 适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HECW1 antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- HECW1 Antibody detects endogenous levels of total HECW1.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human HECW1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product HECW1 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- HECW1 (HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1))
- 别名
- HECW1 (HECW1 产品)
- 别名
- NEDL1 antibody, 9330116H24Rik antibody, AV273951 antibody, E130207I19Rik antibody, Nedl1 antibody, HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 antibody, HECW1 antibody, Hecw1 antibody
- 背景
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Description: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
Gene: HECW1
- 分子量
- 180kDa
- 基因ID
- 23072
- UniProt
- Q76N89
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