GRIA4 抗体
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- 抗原 See all GRIA4 抗体
- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRIA4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- GRIA4 Antibody detects endogenous levels of total GRIA4
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human GRIA4
- 亚型
- IgG
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
- 别名
- GRIA4 (GRIA4 产品)
- 别名
- GLUR4 antibody, GLUR4C antibody, GLURD antibody, GluA4 antibody, GluR4 antibody, GluR4d antibody, GLUR4/D antibody, glur4 antibody, GluR-D antibody, Glur-4 antibody, Glur4 antibody, Gluralpha4 antibody, spkw1 antibody, DKFZp459P0616 antibody, glur4a antibody, gria4 antibody, iGluR4 antibody, ZfGluR4b antibody, fj46g06 antibody, glur4b antibody, wu:fj46g06 antibody, glutamate ionotropic receptor AMPA type subunit 4 antibody, glutamate receptor, ionotropic, AMPA 4 antibody, glutamate receptor, ionotropic, AMPA4 (alpha 4) antibody, glutamate receptor, ionotropic, AMPA 4a antibody, glutamate receptor, ionotropic, AMPA 4b antibody, GRIA4 antibody, gria4 antibody, Gria4 antibody, gria4a antibody, gria4b antibody
- 背景
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Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Gene: GRIA4
- 分子量
- 120 kDa
- 基因ID
- 2893
- UniProt
- P48058
- 途径
- PI3K-Akt Signaling
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