-
- 抗原 See all GDF6 抗体
- GDF6 (Growth Differentiation Factor 6 (GDF6))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This GDF6 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- GDF6 Antibody detects endogenous levels of total GDF6.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human GDF6, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product GDF6 Primary Antibody
-
anti-Growth Differentiation Factor 6 (GDF6) antibody
GDF6 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 6 (GDF6) (AA 336-455) antibodyGDF6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 6 (GDF6) (AA 31-59), (N-Term) antibodyGDF6 适用: 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB14527 unconjugated
anti-Growth Differentiation Factor 6 (GDF6) (AA 326-353), (C-Term) antibodyGDF6 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB15615 unconjugated
anti-Growth Differentiation Factor 6 (GDF6) antibodyGDF6 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 6 (GDF6) (AA 38-67), (N-Term) antibodyGDF6 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 6 (GDF6) (AA 339-454) antibodyGDF6 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- GDF6 (Growth Differentiation Factor 6 (GDF6))
- 别名
- GDF6 (GDF6 产品)
- 别名
- BMP13 antibody, CDMP2 antibody, KFM antibody, KFS antibody, KFS1 antibody, KFSL antibody, LCA17 antibody, MCOP4 antibody, MCOPCB6 antibody, SCDO4 antibody, SGM1 antibody, GDF16 antibody, gdf16 antibody, CDMP-2 antibody, gdf6 antibody, rdr antibody, sb:cb278 antibody, bmp13 antibody, cdmp2 antibody, gdf-6 antibody, kfs antibody, kfsl antibody, sgm1 antibody, growth differentiation factor 6 antibody, growth differentiation factor 6a antibody, growth differentiation factor 6 S homeolog antibody, GDF6 antibody, Gdf6 antibody, gdf6 antibody, gdf6a antibody, gdf6.S antibody
- 背景
-
Description: Growth factor that controls proliferation and cellular differentiation in the retina and bone formation. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map (PubMed:23307924). Required for normal formation of bones and joints in the limbs, skull, digits and axial skeleton. Plays a key role in establishing boundaries between skeletal elements during development. Regulation of GDF6 expression seems to be a mechanism for evolving species-specific changes in skeletal strucutres. Seems to positively regulates differentiation of chondrogenic tissue through the growth factor receptors subunits BMPR1A, BMPR1B, BMPR2 and ACVR2A, leading to the activation of SMAD1-SMAD5-SMAD8 complex. The regulation of chondrogenic differentiation is inhibited by NOG (PubMed:26643732). Also involved in the induction of adipogenesis from mesenchymal stem cells. This mechanism acts through the growth factor receptors subunits BMPR1A, BMPR2 and ACVR2A and the activation of SMAD1-SMAD5-SMAD8 complex and MAPK14/p38 (By similarity).
Gene: GDF6
- 分子量
- 51 kDa
- 基因ID
- 392255
- UniProt
- Q6KF10
-
You are here:
