FAF2 抗体 (Internal Region)
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- 抗原 See all FAF2 抗体
- FAF2 (Fas Associated Factor Family Member 2 (FAF2))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FAF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- FAF2 Antibody detects endogenous levels of total FAF2.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human FAF2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product FAF2 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- FAF2 (Fas Associated Factor Family Member 2 (FAF2))
- 别名
- FAF2 (FAF2 产品)
- 别名
- FAF2 antibody, UBXD8 antibody, ETEA antibody, UBXN3B antibody, 2210404D11Rik antibody, AI462440 antibody, Ubxd8 antibody, mKIAA0887 antibody, 2210404d11rik antibody, RGD1306577 antibody, UBX8 antibody, etea antibody, ubxd8 antibody, ubxn3b antibody, Fas associated factor family member 2 antibody, Fas associated factor family member 2 S homeolog antibody, FAF2 antibody, Faf2 antibody, faf2.S antibody
- 背景
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Description: Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:18711132, PubMed:24215460). By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway (PubMed:26692333). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis (PubMed:23297223).
Gene: FAF2
- 分子量
- 53 kDa
- 基因ID
- 23197
- UniProt
- Q96CS3
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