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EIF3B 抗体

EIF3B 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261481
发货至: 中国
  • 抗原 See all EIF3B 抗体
    EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))
    适用
    • 23
    • 10
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 23
    克隆类型
    • 20
    • 3
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF3B antibody is un-conjugated
    应用范围
    • 12
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    EIF3B Antibody detects endogenous levels of total EIF3B
    交叉反应
    人, 小鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human EIF3B
    亚型
    IgG
    Top Product
    Discover our top product EIF3B Primary Antibody
  • 应用备注
    WB 1:1000-3000 IHC 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))
    别名
    EIF3B (EIF3B 产品)
    别名
    EIF3-ETA antibody, EIF3-P110 antibody, EIF3-P116 antibody, EIF3S9 antibody, PRT1 antibody, AL033316 antibody, AL033334 antibody, AL033369 antibody, AW208965 antibody, D5Wsu45e antibody, Eif3s9 antibody, eif3-eta antibody, eif3-p110 antibody, eif3-p116 antibody, eif3s9 antibody, prt1 antibody, ATEIF3B-2 antibody, EIF3B antibody, EUKARYOTIC TRANSLATION INITIATION FACTOR 3B antibody, F18A17.30 antibody, F18A17_30 antibody, eukaryotic translation initiation factor 3B-2 antibody, DDBDRAFT_0218512 antibody, DDBDRAFT_0233929 antibody, DDB_0218512 antibody, DDB_0233929 antibody, eIF-3-eta antibody, eif3b antibody, wu:fc17c01 antibody, GB10123 antibody, eIF3b antibody, AO090005000892 antibody, CaO19.6584 antibody, eIF3 p90 antibody, eukaryotic translation initiation factor 3 subunit B antibody, eukaryotic translation initiation factor 3, subunit B antibody, eukaryotic translation initiation factor 3B-2 antibody, eukaryotic initiation factor antibody, RNA recognition motif-containing protein RRM antibody, eukaryotic translation initiation factor 3b antibody, eukaryotic translation initiation factor 3 subunit B L homeolog antibody, eukaryotic translation initiation factor 3, subunit Ba antibody, eukaryotic translation initiation factor 3 subunit 9 antibody, translation initiation factor eIF-3 subunit 9 antibody, Eukaryotic translation initiation factor 3 subunit B antibody, translation initiation factor eIF3 subunit b antibody, EIF3B antibody, Eif3b antibody, eif3b antibody, EIF3B-2 antibody, eIF3s9 antibody, eif3B antibody, eif3b.L antibody, eif3ba antibody, LOC410100 antibody, eIF3-S9 antibody, AOR_1_1564174 antibody, VDBG_02490 antibody, PGTG_13070 antibody, Tsp_02250 antibody, eif-3.B antibody, PRT1 antibody
    背景

    Description: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:9388245, PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).

    Gene: EIF3B

    分子量
    116 kDa
    基因ID
    8662
    UniProt
    P55884
    途径
    Ribonucleoprotein Complex Subunit Organization
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