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DNAJB2 抗体 (Internal Region)

DNAJB2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261330
发货至: 中国
  • 抗原 See all DNAJB2 抗体
    DNAJB2 (DnaJ (Hsp40) Homolog, Subfamily B, Member 2 (DNAJB2))
    抗原表位
    • 15
    • 14
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 48
    • 2
    • 2
    • 1
    宿主
    • 44
    • 4
    克隆类型
    • 45
    • 3
    多克隆
    标记
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This DNAJB2 antibody is un-conjugated
    应用范围
    • 28
    • 27
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    DNAJB2 Antibody detects endogenous levels of total DNAJB2.
    预测反应
    Pig,Bovine,Horse,Sheep,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human DNAJB2, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product DNAJB2 Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    DNAJB2 (DnaJ (Hsp40) Homolog, Subfamily B, Member 2 (DNAJB2))
    别名
    DNAJB2 (DNAJB2 产品)
    别名
    MGC78895 antibody, DSMA5 antibody, HSJ-1 antibody, HSJ1 antibody, HSPF3 antibody, 2700059H22Rik antibody, Dnajb10 antibody, Hsj1 antibody, mDj8 antibody, DnaJ heat shock protein family (Hsp40) member B2 L homeolog antibody, DnaJ heat shock protein family (Hsp40) member B2 antibody, dnajb2.L antibody, DNAJB2 antibody, dnajb2 antibody, Dnajb2 antibody
    背景

    Description: Functions as a co-chaperone, regulating the substrate binding and activating the ATPase activity of chaperones of the HSP70/heat shock protein 70 family (PubMed:7957263, PubMed:22219199). In parallel, also contributes to the ubiquitin-dependent proteasomal degradation of misfolded proteins (PubMed:15936278, PubMed:21625540). Thereby, may regulate the aggregation and promote the functional recovery of misfolded proteins like HTT, MC4R, PRKN, RHO and SOD1 and be crucial for many biological processes (PubMed:12754272, PubMed:20889486, PubMed:21719532, PubMed:22396390, PubMed:24023695). Isoform 1 which is localized to the endoplasmic reticulum membranes may specifically function in ER-associated protein degradation of misfolded proteins (PubMed:15936278).

    Gene: DNAJB2

    分子量
    36 kDa
    基因ID
    3300
    UniProt
    P25686
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