CYP26B1 抗体 (Internal Region)
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- 抗原 See all CYP26B1 抗体
- CYP26B1 (Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP26B1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CYP26B1 Antibody detects endogenous levels of total CYP26B1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CYP26B1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CYP26B1 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CYP26B1 (Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))
- 别名
- CYP26B1 (CYP26B1 产品)
- 别名
- cyp26b1 antibody, cyp26a2 antibody, p450rai-2 antibody, CYP26A2 antibody, P450RAI-2 antibody, P450RAI2 antibody, RHFCA antibody, CP26 antibody, fc21d03 antibody, wu:fc21d03 antibody, wu:fc26h10 antibody, zgc:76999 antibody, cytochrome P450 26B1 antibody, cytochrome P450 family 26 subfamily B member 1 L homeolog antibody, cytochrome P450 family 26 subfamily B member 1 antibody, cytochrome P450, family 26, subfamily B, polypeptide 1 antibody, cytochrome P450, family 26, subfamily b, polypeptide 1 antibody, CpipJ_CPIJ002537 antibody, cyp26b1.L antibody, CYP26B1 antibody, cyp26b1 antibody, Cyp26b1 antibody
- 背景
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Description: Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Involved in the specific inactivation of all-trans-retinoic acid (all-trans-RA), with a preference for the following substrates: all-trans-RA > 9-cis-RA > 13-cis-RA. Generates several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA, and 18-OH-RA. Essential for postnatal survival. Plays a central role in germ cell development: acts by degrading RA in the developing testis, preventing STRA8 expression, thereby leading to delay of meiosis. Required for the maintenance of the undifferentiated state of male germ cells during embryonic development in Sertoli cells, inducing arrest in G0 phase of the cell cycle and preventing meiotic entry. Plays a role in skeletal development, both at the level of patterning and in the ossification of bone and the establishment of some synovial joints.
Gene: CYP26B1
- 分子量
- 58-60 kDa
- 基因ID
- 56603
- UniProt
- Q9NR63
- 途径
- Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Monocarboxylic Acid Catabolic Process
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