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- 抗原 See all CYFIP1 抗体
- CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYFIP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- CYFIP1 Antibody detects endogenous levels of total CYFIP1.
- 预测反应
- Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CYFIP1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CYFIP1 Primary Antibody
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anti-Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) (AA 320-449) antibody
CYFIP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) (AA 524-558) antibodyCYFIP1 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB47040 unconjugated
anti-Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) (AA 1-270) antibodyCYFIP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))
- 别名
- CYFIP1 (CYFIP1 产品)
- 别名
- TUBGCP5 antibody, P140SRA-1 antibody, SHYC antibody, SRA1 antibody, E030028J09Rik antibody, P140sra1 antibody, Shyc antibody, Sra-1 antibody, Sra1 antibody, l(7)1Rl antibody, l71Rl antibody, l7Rl1 antibody, mKIAA0068 antibody, pl-1 antibody, CY antibody, CYFIP antibody, fb15a06 antibody, wu:fb15a06 antibody, cytoplasmic FMR1 interacting protein 1 antibody, CYFIP1 antibody, cyfip1 antibody, Cyfip1 antibody
- 背景
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Description: Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). May act as an invasion suppressor in cancers.
Gene: CYFIP1
- 分子量
- 145 kDa
- 基因ID
- 23191
- UniProt
- Q7L576
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