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- 抗原 See all SS18L1 抗体
- SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SS18L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- CREST antibody detects endogenous levels of CREST.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CREST.
- 亚型
- IgG
- Top Product
- Discover our top product SS18L1 Primary Antibody
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anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 47-396) antibody
SS18L1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) antibodySS18L1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 251-300) antibodySS18L1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 200-396) antibodySS18L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 90-270) antibodySS18L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (Middle Region) antibodySS18L1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
- 别名
- CREST (SS18L1 产品)
- 别名
- crest antibody, CREST antibody, LP2261 antibody, A230053O16Rik antibody, SS18L1, nBAF chromatin remodeling complex subunit antibody, synovial sarcoma translocation gene on chromosome 18-like 1 antibody, synovial sarcoma translocation gene on chromosome 18-like 1 S homeolog antibody, SS18, nBAF chromatin remodeling complex subunit like 1 antibody, SS18L1 antibody, ss18l1 antibody, ss18l1.S antibody, Ss18l1 antibody
- 背景
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Description: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity).
Gene: SS18L1
- 分子量
- 50 kDa
- 基因ID
- 26039
- UniProt
- O75177
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