C-Type Lectin Domain Family 6, Member A (CLEC6A) (Internal Region) 抗体
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- 抗原 See all C-Type Lectin Domain Family 6, Member A (CLEC6A) 抗体
- C-Type Lectin Domain Family 6, Member A (CLEC6A)
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CLEC6A Antibody detects endogenous levels of total CLEC6A.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CLEC6A, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CLEC6A Primary Antibody
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- C-Type Lectin Domain Family 6, Member A (CLEC6A)
- 别名
- CLEC6A (CLEC6A 产品)
- 别名
- CLEC4N antibody, CLECSF10 antibody, CLEC6A antibody, C-type lectin domain containing 6A antibody, C-type lectin domain family 6, member A antibody, CLEC6A antibody, Clec6a antibody
- 背景
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Description: Binds high-mannose carbohydrates in a Ca2+-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway (By similarity).
Gene: CLEC6A
- 分子量
- 24 kDa
- 基因ID
- 93978
- UniProt
- Q6EIG7
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