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CLASP2 抗体

CLASP2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260858
发货至: 中国
  • 抗原 See all CLASP2 抗体
    CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This CLASP2 antibody is un-conjugated
    应用范围
    • 53
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    Western Blotting (WB), ELISA
    特异性
    CLASP2 Antibody detects endogenous levels of total CLASP2
    交叉反应
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CLASP2
    亚型
    IgG
    Top Product
    Discover our top product CLASP2 Primary Antibody
  • 应用备注
    WB 1:1000-3000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))
    别名
    CLASP2 (CLASP2 产品)
    别名
    zgc:77279 antibody, DKFZp459M112 antibody, 1500004F14Rik antibody, 8030404L10Rik antibody, C77448 antibody, CLASP2beta antibody, mKIAA0627 antibody, cytoplasmic linker associated protein 2 antibody, CLIP associating protein 2 antibody, clasp2 antibody, CLASP2 antibody, Clasp2 antibody
    背景

    Description: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.

    Gene: CLASP2

    分子量
    141kDa
    基因ID
    23122
    UniProt
    O75122
    途径
    Microtubule Dynamics, Maintenance of Protein Location
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