CBX2 抗体 (Internal Region)
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- 抗原 See all CBX2 抗体
- CBX2 (Chromobox Homolog 2 (CBX2))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBX2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- CBX2 Antibody detects endogenous levels of total CBX2.
- 预测反应
- Pig,Bovine,Sheep,Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CBX2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CBX2 Primary Antibody
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CBX2 (Chromobox Homolog 2 (CBX2))
- 别名
- CBX2 (CBX2 产品)
- 别名
- cbx2 antibody, M33 antibody, pc1 antibody, wu:fd20e09 antibody, zgc:103563 antibody, MOD2 antibody, pc antibody, CDCA6 antibody, SRXY5 antibody, cdca6 antibody, m33 antibody, chromobox 2 antibody, chromobox homolog 2 (Drosophila Pc class) antibody, chromobox 2 L homeolog antibody, cbx2 antibody, CBX2 antibody, Cbx2 antibody, cbx2.L antibody
- 背景
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Description: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:21282530). Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) (By similarity). Plays a role in the lineage differentiation of the germ layers in embryonic development (By similarity). Involved in sexual development, acting as activator of NR5A1 expression (PubMed:19361780).
Gene: CBX2
- 分子量
- 56 kDa
- 基因ID
- 84733
- UniProt
- Q14781
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