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CAMK1 抗体 (Internal Region)

Name: CAMK1 抗体 (Internal Region)
SKU: ABIN6260424
Availability: OutOfStock

CAMK1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of CAMK1 using Jurkat whole lysates. (CAMK1 抗体 (Internal Region))

1 image

产品编号 ABIN6260424

发货至: 中国

Datasheet as PDF

抗原 See all CAMK1 抗体

CAMK1 (Calcium/calmodulin-Dependent Protein Kinase I (CAMK1))
抗原表位
11

7

6

5

2

2

1

1

1

1

1

1

1

1

1

1

1
Internal Region
适用
46

32

31

8

4

2

2

2

1

1

1

1

1
人
宿主
41

4

1

1
兔
Compatible Secondaries
克隆类型
42

5
多克隆
标记
31

3

3

2

1

1

1

1

1

1

1

1
This CAMK1 antibody is un-conjugated
应用范围
33

21

20

7

7

3

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

CaMK1 alpha Antibody detects endogenous levels of total CaMK1 alpha.

预测反应

Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human CaMK1 alpha, corresponding to a region within the internal amino acids.

亚型

IgG

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anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (C-Term) antibody
CAMK1 适用: 人, 小鼠, 大鼠, 灵长类, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (AA 1-93) antibody
CAMK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (AA 166-265) antibody
CAMK1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (AA 271-370) antibody
CAMK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B6 unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (AA 341-370), (C-Term) antibody
CAMK1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p) 宿主: 兔 Polyclonal RB1255 unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (AA 143-192), (pThr177) antibody
CAMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (pSer177) antibody
CAMK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (C-Term) antibody
CAMK1 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) antibody
CAMK1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

CAMK1 (Calcium/calmodulin-Dependent Protein Kinase I (CAMK1))

别名

CAMK1 (CAMK1 产品)

别名

CAMKI antibody, Camki antibody, Gaip antibody, CG1495 antibody, Calcium/calmodulin-dependent protein kinase antibody, CamKI antibody, Dmel\\CG1495 antibody, caMKI antibody, camKI antibody, dCKI antibody, AI505105 antibody, CaMKIalpha antibody, D6Ertd263e antibody, cam-kia antibody, camk1 antibody, camkI antibody, calcium/calmodulin dependent protein kinase I antibody, calcium/calmodulin-dependent protein kinase I antibody, Calcium/calmodulin-dependent protein kinase I antibody, calcium/calmodulin-dependent protein kinase I L homeolog antibody, CAMK1 antibody, Camk1 antibody, CaMKI antibody, camk1.L antibody

背景

Description: Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, regulates transcription activators activity, cell cycle, hormone production, cell differentiation, actin filament organization and neurite outgrowth. Recognizes the substrate consensus sequence [MVLIF]-x-R-x2-[ST]-x3-[MVLIF]. Regulates axonal extension and growth cone motility in hippocampal and cerebellar nerve cells. Upon NMDA receptor-mediated Ca2+ elevation, promotes dendritic growth in hippocampal neurons and is essential in synapses for full long-term potentiation (LTP) and ERK2-dependent translational activation. Downstream of NMDA receptors, promotes the formation of spines and synapses in hippocampal neurons by phosphorylating ARHGEF7/BETAPIX on 'Ser-694', which results in the enhancement of ARHGEF7 activity and activation of RAC1. Promotes neuronal differentiation and neurite outgrowth by activation and phosphorylation of MARK2 on 'Ser-91', 'Ser-92', 'Ser-93' and 'Ser-294'. Promotes nuclear export of HDAC5 and binding to 14-3-3 by phosphorylation of 'Ser-259' and 'Ser-498' in the regulation of muscle cell differentiation. Regulates NUMB-mediated endocytosis by phosphorylation of NUMB on 'Ser-276' and 'Ser-295'. Involved in the regulation of basal and estrogen-stimulated migration of medulloblastoma cells through ARHGEF7/BETAPIX phosphorylation (By similarity). Is required for proper activation of cyclin-D1/CDK4 complex during G1 progression in diploid fibroblasts. Plays a role in K+ and ANG2-mediated regulation of the aldosterone synthase (CYP11B2) to produce aldosterone in the adrenal cortex. Phosphorylates EIF4G3/eIF4GII. In vitro phosphorylates CREB1, ATF1, CFTR, MYL9 and SYN1/synapsin I.
Gene: CAMK1

分子量

41 kDa

基因ID

8536

UniProt

Q14012

途径

Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Smooth Muscle Cell Migration