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BAK1 抗体 (N-Term)

This anti-BAK1 antibody is a 兔 多克隆 antibody detecting BAK1 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6260195
发货至: 中国

Quick Overview for BAK1 抗体 (N-Term) (ABIN6260195)

抗原

See all BAK1 抗体
BAK1 (BCL2-Antagonist/killer 1 (BAK1))

适用

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人, 小鼠, 大鼠

宿主

  • 70
  • 8
  • 2
  • 1

克隆类型

  • 61
  • 20
多克隆

标记

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  • 1
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  • 1
  • 1
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  • 1
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This BAK1 antibody is un-conjugated

应用范围

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  • 11
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  • 5
  • 3
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 16
    • 12
    • 8
    • 4
    • 3
    • 3
    • 3
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    • 2
    • 1
    • 1
    • 1
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    • 1
    N-Term

    特异性

    Bak Antibody detects endogenous levels of total Bak.

    预测反应

    Bovine,Horse,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human Bak, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    BAK1 (BCL2-Antagonist/killer 1 (BAK1))

    别名

    BAK1

    背景

    Description: Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases.

    Gene: BAK1

    分子量

    25kDa

    基因ID

    578

    UniProt

    Q16611

    途径

    Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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