Antizyme Inhibitor 1 抗体 (Internal Region)
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- 抗原 See all Antizyme Inhibitor 1 (AZIN1) 抗体
- Antizyme Inhibitor 1 (AZIN1)
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抗原表位
- Internal Region
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Antizyme Inhibitor 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Antizyme inhibitor 1 Antibody detects endogenous levels of total Antizyme inhibitor 1.
- 预测反应
- Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Antizyme inhibitor 1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product AZIN1 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- Antizyme Inhibitor 1 (AZIN1)
- 别名
- AZIN1 (AZIN1 产品)
- 别名
- OAZI antibody, OAZIN antibody, ODC1L antibody, 1700085L02Rik antibody, AI414949 antibody, Oazi antibody, Oazin antibody, AZIN1 antibody, azin1 antibody, oazin antibody, wu:fj32d12 antibody, MGC81852 antibody, wu:fc93f10 antibody, zgc:110131 antibody, antizyme inhibitor 1 antibody, antizyme inhibitor 1b antibody, antizyme inhibitor 1 L homeolog antibody, antizyme inhibitor 1a antibody, AZIN1 antibody, Azin1 antibody, azin1b antibody, azin1.L antibody, azin1 antibody, azin1a antibody
- 背景
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Description: Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240, PubMed:26305948). Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240).
Gene: AZIN1
- 分子量
- 49.5 kDa
- 基因ID
- 51582
- UniProt
- O14977
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