GNB5 抗体 (Internal Region)
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- 抗原 See all GNB5 抗体
- GNB5 (Guanine Nucleotide Binding Protein (G Protein), beta 5 (GNB5))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GNB5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- GNB5 Antibody detects endogenous levels of total GNB5.
- 预测反应
- Pig,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human GNB5, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product GNB5 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- GNB5 (Guanine Nucleotide Binding Protein (G Protein), beta 5 (GNB5))
- 别名
- GNB5 (GNB5 产品)
- 别名
- GB5 antibody, GBS antibody, Gbeta5 antibody, flr antibody, G protein subunit beta 5 antibody, guanine nucleotide binding protein (G protein), beta 5 antibody, GNB5 antibody, Gnb5 antibody
- 背景
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Description: Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D2 dopamine receptors (PubMed:27677260). May play an important role in neuronal signaling, including in the parasympathetic, but not sympathetic, control of heart rate (By similarity).
Gene: GNB5
- 分子量
- 40 kDa
- 基因ID
- 10681
- UniProt
- O14775
- 途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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