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GLRB 抗体 (Internal Region)

GLRB 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258906
发货至: 中国
  • 抗原 See all GLRB 抗体
    GLRB (Glycine Receptor, beta (GLRB))
    抗原表位
    • 15
    • 10
    • 9
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 36
    • 32
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 42
    • 2
    克隆类型
    • 42
    • 2
    多克隆
    标记
    • 17
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLRB antibody is un-conjugated
    应用范围
    • 39
    • 23
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    GLRB Antibody detects endogenous levels of total GLRB.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human GLRB, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product GLRB Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    GLRB (Glycine Receptor, beta (GLRB))
    别名
    GLRB (GLRB 产品)
    别名
    HKPX2 antibody, glrb antibody, MGC145156 antibody, AI853901 antibody, Glyrb antibody, spa antibody, spastic antibody, glrb2 antibody, zgc:101041 antibody, glycine receptor beta antibody, glycine receptor, beta antibody, glycine receptor, beta subunit antibody, glycine receptor, beta b antibody, GLRB antibody, Glrb antibody, glrb antibody, glrbb antibody
    背景

    Description: Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).

    Gene: GLRB

    分子量
    56 kDa
    基因ID
    2743
    UniProt
    P48167
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