FZD2 抗体 (Internal Region)
Quick Overview for FZD2 抗体 (Internal Region) (ABIN6258789)
抗原
See all FZD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- FZD2 Antibody detects endogenous levels of total FZD2.
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预测反应
- Pig,Bovine,Horse,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human FZD2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Frizzled Family Receptor 2 (FZD2) (Internal Region) antibody
Verified FZD2 适用: 人 WB, ELISA, IF, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (Extracellular Domain) antibodyFZD2 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, Hamster, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (N-Term) antibodyFZD2 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, Hamster, Pig, 猴, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (AA 192-245) antibodyFZD2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C8 unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (N-Term) antibodyFZD2 适用: 人, 大鼠, 小鼠, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) antibodyFZD2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (N-Term) antibodyFZD2 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (AA 201-250) antibodyFZD2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (AA 192-205), (Extracellular) antibodyFZD2 适用: 大鼠 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- FZD2 (Frizzled Family Receptor 2 (FZD2))
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别名
- FZD2
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背景
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Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Gene: FZD2
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分子量
- 55 kDa
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基因ID
- 2535
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UniProt
- Q14332
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途径
- WNT signaling
抗原
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