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- 抗原 See all VPS4B (vps4b) 抗体
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VPS4B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- VPS4B Antibody detects endogenous levels of total VPS4B.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human VPS4B, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product vps4b Primary Antibody
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anti-Vacuolar Protein Sorting 4 Homolog B (vps4b) (AA 1-117) antibody
vps4b 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 4 Homolog B (vps4b) (AA 1-444) antibodyvps4b 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 4 Homolog B (vps4b) (AA 70-119) antibodyvps4b 适用: 人, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 4 Homolog B (vps4b) (AA 1-130) antibodyvps4b 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 4 Homolog B (vps4b) (AA 304-332), (C-Term) antibodyvps4b 适用: 人 WB 宿主: 兔 Polyclonal RB32061 unconjugated
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- 应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
- 别名
- VPS4B (vps4b 产品)
- 别名
- zgc:63682 antibody, vps4a antibody, SKD1 antibody, SKD1B antibody, VPS4-2 antibody, 8030489C12Rik antibody, Skd1 antibody, vacuolar protein sorting 4 homolog B antibody, vacuolar protein sorting 4 homolog B S homeolog antibody, vacuolar protein sorting 4b homolog B (S. cerevisiae) antibody, vacuolar protein sorting 4 homolog B (S. cerevisiae) antibody, vacuolar protein sorting 4B antibody, Vps4b antibody, vps4b.S antibody, vps4b antibody, VPS4B antibody
- 背景
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Description: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). VPS4A/B are required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).
Gene: VPS4B
- 分子量
- 49 kDa
- 基因ID
- 9525
- UniProt
- O75351
- 途径
- Microtubule Dynamics, CXCR4-mediated Signaling Events
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