MAPK10 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for MAPK10 抗体 (C-Term) (ABIN6257975)
抗原
See all MAPK10 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- JNK3 Antibody detects endogenous levels of total JNK3.
-
预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Chicken
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human MAPK10, corresponding to a region within C-terminal amino acids.
-
亚型
- IgG
-
-
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 175-464) antibody
MAPK10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) antibodyKD Validated MAPK10 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB320 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 180-329) antibodyMAPK10 适用: 人, 大鼠 WB, ELISA 宿主: 小鼠 Monoclonal 2B10H12 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 88-332) antibodyMAPK10 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 133-316) antibodyMAPK10 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 28-233) antibodyMAPK10 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 10E4A4 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (C-Term) antibodyMAPK10 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (C-Term) antibodyMAPK10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 1-319) antibodyMAPK10 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E12-1F7 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) antibodyMAPK10 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 8A5D11 unconjugated
-
-
应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
-
别名
- MAPK10
-
背景
-
Description: Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK10/JNK3. In turn, MAPK10/JNK3 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. Plays regulatory roles in the signaling pathways during neuronal apoptosis. Phosphorylates the neuronal microtubule regulator STMN2. Acts in the regulation of the amyloid-beta precursor protein/APP signaling during neuronal differentiation by phosphorylating APP. Participates also in neurite growth in spiral ganglion neurons. Phosphorylates the CLOCK-ARNTL/BMAL1 heterodimer and plays a role in the photic regulation of the circadian clock (PubMed:22441692).
Gene: MAPK10
-
分子量
- 48 kDa
-
基因ID
- 5602
-
UniProt
- P53779
-
途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
抗原
-
