LRP8 抗体 (Internal Region)
-
- 抗原 See all LRP8 抗体
- LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This LRP8 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- LRP8 Antibody detects endogenous levels of total LRP8.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human LRP8, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product LRP8 Primary Antibody
-
anti-Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) (AA 851-963) antibody
LRP8 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) (AA 42-182) antibodyLRP8 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7G12E2 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) (AA 696-941) antibodyLRP8 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) (AA 83-170) antibodyLRP8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H2 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) (AA 934-963) antibodyLRP8 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) (AA 131-332) antibodyLRP8 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) (AA 83-170) antibodyLRP8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) (AA 395-444) antibodyLRP8 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) (C-Term) antibodyLRP8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) (AA 650-699) antibodyLRP8 适用: 人, 小鼠, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
- 别名
- LRP8 (LRP8 产品)
- 别名
- LRP8 antibody, APOER2 antibody, HSZ75190 antibody, LRP-8 antibody, MCI1 antibody, 4932703M08Rik antibody, AA921429 antibody, AI848122 antibody, ApoER2 antibody, Lr8b antibody, LR8B antibody, LDL receptor related protein 8 antibody, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor antibody, LRP8 antibody, Lrp8 antibody
- 背景
-
Description: Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Binds the endoplasmic reticulum resident receptor-associated protein (RAP). Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature. Highly expressed in the initial segment of the epididymis, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), two proteins required for sperm maturation. May also function as an endocytic receptor. Not required for endocytic uptake of SEPP1 in the kidney which is mediated by LRP2 (By similarity).
Gene: LRP8
- 分子量
- 100 kDa
- 基因ID
- 7804
- UniProt
- Q14114
-
