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ARHGAP18 抗体 (Internal Region)

ARHGAP18 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257900
发货至: 中国
  • 抗原 See all ARHGAP18 抗体
    ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))
    抗原表位
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 24
    • 5
    • 5
    • 1
    人, 大鼠
    宿主
    • 24
    克隆类型
    • 24
    多克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    This ARHGAP18 antibody is un-conjugated
    应用范围
    • 20
    • 17
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    RHG18 Antibody detects endogenous levels of total RHG18.
    预测反应
    Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RHG18, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ARHGAP18 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))
    别名
    ARHGAP18 (ARHGAP18 产品)
    别名
    4833419J07Rik antibody, AI314906 antibody, AI843501 antibody, MacGAP antibody, SENEX antibody, bA307O14.2 antibody, MGC146282 antibody, DKFZp469I1011 antibody, Rho GTPase activating protein 18 antibody, Rho GTPase activating protein 18 L homeolog antibody, Arhgap18 antibody, ARHGAP18 antibody, arhgap18 antibody, arhgap18.L antibody
    背景

    Description: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595).

    Gene: ARHGAP18

    分子量
    75 kDa
    基因ID
    93663
    UniProt
    Q8N392
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