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- 抗原 See all PHACTR4 抗体
- PHACTR4 (Phosphatase and Actin Regulator 4 (PHACTR4))
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抗原表位
- Internal Region
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PHACTR4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- PHACTR4 Antibody detects endogenous levels of total PHACTR4.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PHACTR4, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PHACTR4 Primary Antibody
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anti-Phosphatase and Actin Regulator 4 (PHACTR4) antibody
PHACTR4 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- PHACTR4 (Phosphatase and Actin Regulator 4 (PHACTR4))
- 别名
- PHACTR4 (PHACTR4 产品)
- 别名
- 3110001B12Rik antibody, AI527228 antibody, AW495572 antibody, C330013F19Rik antibody, N28169 antibody, mKIAA4120 antibody, phactr4 antibody, zgc:63484 antibody, zgc:123224 antibody, phosphatase and actin regulator 4 antibody, phosphatase and actin regulator 4b antibody, phosphatase and actin regulator 4 L homeolog antibody, phosphatase and actin regulator 4 S homeolog antibody, phosphatase and actin regulator 4a antibody, Phactr4 antibody, phactr4b antibody, PHACTR4 antibody, phactr4.L antibody, phactr4.S antibody, Tsp_08786 antibody, phactr4 antibody, phactr4a antibody
- 背景
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Description: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin (COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway (By similarity).
Gene: PHACTR4
- 分子量
- 80 kDa
- 基因ID
- 65979
- UniProt
- Q8IZ21
- 途径
- Tube Formation
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