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TLK1 抗体 (C-Term)

This anti-TLK1 antibody is a 兔 多克隆 antibody detecting TLK1 in WB 和 ELISA. Suitable for 人 和 大鼠.
产品编号 ABIN6257779
发货至: 中国

Quick Overview for TLK1 抗体 (C-Term) (ABIN6257779)

抗原

See all TLK1 抗体
TLK1 (Tousled-Like Kinase 1 (TLK1))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TLK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    C-Term

    特异性

    TLK1 Antibody detects endogenous levels of total TLK1.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human TLK1, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    TLK1 (Tousled-Like Kinase 1 (TLK1))

    别名

    TLK1

    背景

    Description: Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.

    Gene: TLK1

    分子量

    87 kDa

    基因ID

    9874

    UniProt

    Q9UKI8
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