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- 抗原 See all CCAR1 抗体
- CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CCAR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- CCAR1 Antibody detects endogenous levels of total CCAR1.
- 预测反应
- Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CCAR1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CCAR1 Primary Antibody
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anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) (AA 1-200) antibody
CCAR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) antibodyCCAR1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) (AA 1-200) antibodyCCAR1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) (AA 1-200) antibodyCCAR1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) (Internal Region) antibodyVerified CCAR1 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) antibodyCCAR1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))
- 别名
- CCAR1 (CCAR1 产品)
- 别名
- CCAR1 antibody, KIAA1967 antibody, ccar1 antibody, MGC81663 antibody, zehn1480 antibody, hm:zehn1480 antibody, si:dkey-85g17.2 antibody, RP11-437A18.1 antibody, CARP-1 antibody, 2610511G16Rik antibody, 9430036H15Rik antibody, Carp1 antibody, RGD1560358 antibody, cell division cycle and apoptosis regulator 1 antibody, cell division cycle and apoptosis regulator 1 L homeolog antibody, cell division cycle and apoptosis regulator protein 1 antibody, CCAR1 antibody, ccar1.L antibody, LOC5575286 antibody, ccar1 antibody, LOC409891 antibody, Ccar1 antibody
- 背景
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Description: Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation (PubMed:12816952). In association with CALCOCO1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781). Can act as a both a coactivator and corepressor of AR-mediated transcription. Contributes to chromatin looping and AR transcription complex assembly by stabilizing AR-GATA2 association on chromatin and facilitating MED1 and RNA polymerase II recruitment to AR-binding sites. May play an important role in the growth and tumorigenesis of prostate cancer cells (PubMed:23887938).
Gene: CCAR1
- 分子量
- ?132 kDa
- 基因ID
- 55749
- UniProt
- Q8IX12
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