ELL2 抗体 (Internal Region)
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- 抗原 See all ELL2 抗体
- ELL2 (Elongation Factor, RNA Polymerase II, 2 (ELL2))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ELL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- ELL2 Antibody detects endogenous levels of total ELL2.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ELL2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ELL2 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- ELL2 (Elongation Factor, RNA Polymerase II, 2 (ELL2))
- 别名
- ELL2 (ELL2 产品)
- 别名
- cb244 antibody, fb78f03 antibody, sb:cb244 antibody, im:3814960 antibody, wu:fb78f03 antibody, xell2 antibody, MGC82755 antibody, ELL2 antibody, elongation factor for RNA polymerase II 2 antibody, elongation factor, RNA polymerase II, 2 antibody, elongation factor, RNA polymerase II 2 S homeolog antibody, elongation factor, RNA polymerase II 2 antibody, elongation factor RNA polymerase II 2 antibody, ELL2 antibody, ell2 antibody, ell2.S antibody, Ell2 antibody
- 背景
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Description: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane-specific to secretory IgH mRNA expression.
Gene: ELL2
- 分子量
- 72 kDa
- 基因ID
- 22936
- UniProt
- O00472
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